I1 | New regulations on veterinary medicinal products – Impact on veterinary medicine
نویسندگان
چکیده
منابع مشابه
Committee for Veterinary Medicinal Products
Article 4 of Council Directive 81/851/EEC requires that a Member State shall not authorise the placing on the market of a veterinary medicinal product intended for administration to food producing animals [...] unless the active substance [...] contained in the product: a) were authorised for use in other veterinary medicinal products in the Member State concerned on the day of entry into force...
متن کاملCommittee for Veterinary Medicinal Products
1. Morantel (1,4,5,6-tetrahydro-1-methyl-2-[2-(3-methyl-2-thienyl)ethenyl pyrimidine) is a tetrahydro-pyrimidine anthelmintic, differing from the related analogue pyrantel by the presence of a methyl group on the thiophene ring. It is intended to treat roundworms and tapeworms. It is administered in lactating and non lactating cattle as morantel tartrate as a slow-release bolus (11.8 g morantel...
متن کاملCommittee for Veterinary Medicinal Products
1. Lincomycin is an antibiotic derived from Streptomyces lincolnensis. It belongs to the lincosamide group which also includes pirlimycin and clindamycin. In veterinary medicine, it is used in monopreparations and in combination product with other antibiotics such as spectinomycin, sulfadimidine and gentamicin. It is administered to poultry orally, sometimes in the feed or drinking water, at do...
متن کاملCommittee for Medicinal Products for Veterinary Use
5. Thiabendazole and other benzimidazole anthelmintics act by binding strongly to tubulin in the absorptive cells in the gut of parasitic worms. This interferes with the uptake of nutrients and the worms effectively starve to death. The host is less affected as the binding to mammalian tubulin is less strong and is reversible. Another pharmacological study showed that single oral doses of 25 to...
متن کاملCommittee for Medicinal Products for Veterinary Use
2. The Committee for Medicinal Products for Veterinary Use (CVMP) previously considered triclabendazole and agreed a toxicological ADI of 0.0015 mg/kg bw (i.e. 0.09 mg/person) based on the basis of the increased postpartum mortality of the F2 generation in the two-generation rat reproduction study (NOEL equal to 0.15 mg/kg bw/day) using a safety factor of 100. A validated analytical method base...
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ژورنال
عنوان ژورنال: Journal of Veterinary Pharmacology and Therapeutics
سال: 2023
ISSN: ['1365-2885', '0140-7783']
DOI: https://doi.org/10.1111/jvp.13132